Integrated analysis of coding genes and non-coding RNAs during hair follicle cycle of cashmere goat (Capra hircus).

ABSTRACT:

Background

Cashmere growth is a seasonal and cyclic phenomenon under the control of photoperiod and multiple stimulatory and inhibitory signals. Beyond relevant coding genes, microRNA (miRNA) and long non coding RNA (lncRNA) play an indispensable role in hair follicle (HF) development and skin homeostasis. Furthermore, the influence of lncRNA upon miRNA function is also rapidly emerging. However, little is known about miRNAs, lncRNAs and their functions as well as their interactions on cashmere development and cycling.

Result

Here, based on lncRNA and miRNA high-throughput sequencing and bioinformatics analysis, we have identified 1108 lncRNAs and 541 miRNAs in cashmere goat skin during anagen and telogen. Compared with telogen, 1388 coding genes, 41 lncRNAs and 15 miRNAs we

SUBMITTER: Wang S 

PROVIDER: S-EPMC5637055 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature