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The association between sex hormone-binding globulin and type 2 diabetes in Nigerian men.


ABSTRACT:

Background

Epidemiological studies have shown that sex hormone-binding globulin (SHBG) has a role in glucose homeostasis in both men and women. However, a prospective study on Japanese-American subjects concluded that SHBG was not a significant risk factor in either men or women, suggesting ethnic differences. We were not aware of any evaluation of SHBG in subjects of African ancestry.

Objectives

We investigated the association between SHBG and insulin resistance in type 2 diabetic diabetic men in a hospital in Nigeria.

Method

Forty-eight male subjects with type 2 diabetes and 20 non-diabetic male subjects were recruited in this cross-sectional hospital-based study by the convenient sampling method. Height and circumferences around the waist and hip were measured to t

SUBMITTER: Abbiyesuku FM 

PROVIDER: S-EPMC5637783 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature