Copy number increases of transposable elements and protein-coding genes in an invasive fish of hybrid origin.

ABSTRACT: Evolutionary dynamics of structural genetic variation in lineages of hybrid origin is not well explored, although structural mutations may increase in controlled hybrid crosses. We therefore tested whether structural variants accumulate in a fish of recent hybrid origin, invasive Cottus, relative to both parental species Cottus rhenanus and Cottus perifretum. Copy-number variation in exons of 10,979 genes was assessed using comparative genome hybridization arrays. Twelve genes showed significantly higher copy numbers in invasive Cottus compared to both parents. This coincided with increased expression for three genes related to vision, detoxification and muscle development, suggesting possible gene dosage effects. Copy number increases of putative transposons were assessed by comparative m

SUBMITTER: Dennenmoser S 

PROVIDER: S-EPMC5638112 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature