Actinide bioimaging in tissues: Comparison of emulsion and solid track autoradiography techniques with the iQID camera.

ABSTRACT: This work presents a comparison of three autoradiography techniques for imaging biological samples contaminated with actinides: emulsion-based, plastic-based autoradiography and a quantitative digital technique, the iQID camera, based on the numerical analysis of light from a scintillator screen. In radiation toxicology it has been important to develop means of imaging actinide distribution in tissues as these radionuclides may be heterogeneously distributed within and between tissues after internal contamination. Actinide distribution determines which cells are exposed to alpha radiation and is thus potentially critical for assessing absorbed dose. The comparison was carried out by generating autoradiographs of the same biological samples contaminated with actinides with the three autorad

SUBMITTER: Lamart S 

PROVIDER: S-EPMC5638496 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature