A clinical severity scoring system for visceral leishmaniasis in immunocompetent patients in South Sudan.

ABSTRACT:

Background

South Sudan is one of the most endemic countries for visceral leishmaniasis (VL), and is frequently affected by large epidemics. In resource-limited settings, clinicians require a simple clinical tool to identify VL patients who are at increased risk of dying, and who need specialised treatment with liposomal amphotericin B and other supportive care. The aim of this study was to develop and validate a clinical severity scoring system based on risk factors for death in VL patients in South Sudan.

Methods

A retrospective analysis was conducted of data from a cohort of 6,633 VL patients who were treated in the Médecins Sans Frontières (MSF) hospital in Lankien between July 2013 and June 2015. Risk factors for death during treatment were identified using multivariable

SUBMITTER: Kamink SS 

PROVIDER: S-EPMC5638606 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature