Factors in Early Adolescence Associated With a Mole-Prone Phenotype in Late Adolescence.

ABSTRACT:

Importance

Nevi are important phenotypic risk factors for melanoma in adults. Few studies have examined the constitutional and behavioral factors associated with a mole-prone phenotype in adolescents.

Objective

To identify host, behavioral, and dermoscopic factors in early adolescence (age, 14 years) that are associated with a mole-prone phenotype in late adolescence (age, 17 years).

Design, setting, and participants

A prospective observational cohort study from the Study of Nevi in Children was conducted from January 1, 2009, to December 31, 2014, with a 2- to 3-year follow-up. A total of 569 students from the school system in Framingham, Massachusetts, were enrolled in the 8th or 9th grade (baseline; mean [SD] age, 14.4 [0.7] years). The overall retention rate was 7

SUBMITTER: Xu H 

PROVIDER: S-EPMC5638685 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature