Emergence and loss of spliceosomal twin introns.

ABSTRACT:

Background

In the primary transcript of nuclear genes, coding sequences-exons-usually alternate with non-coding sequences-introns. In the evolution of spliceosomal intron-exon structure, extant intron positions can be abandoned and new intron positions can be occupied. Spliceosomal twin introns ("stwintrons") are unconventional intervening sequences where a standard "internal" intron interrupts a canonical splicing motif of a second, "external" intron. The availability of genome sequences of more than a thousand species of fungi provides a unique opportunity to study spliceosomal intron evolution throughout a whole kingdom by means of molecular phylogenetics.

Results

A new stwintron was encountered in Aspergillus nidulans and Aspergillus niger. It is present ac

SUBMITTER: Flipphi M 

PROVIDER: S-EPMC5639578 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature