Chromatin states responsible for the regulation of differentially expressed genes under ⁶⁰Co~γ ray radiation in rice.

ABSTRACT:

Background

The role of histone modifications in the DNA damage response has been extensively studied in non-plant systems, including mammals and yeast. However, there is a lack of detailed evidence showing how chromatin dynamics, either an individual mark or combined chromatin states, participate in regulating differentially expressed genes in the plant DNA damage response.

Results

In this study, we used RNA-seq and ChIP-seq to show that differentially expressed genes (DEGs), in response to ionizing radiation (IR), might be involved in different pathways responsible for the DNA damage response. Moreover, chromatin structures associated with promoters, exons and intergenic regions are significantly affected by IR. Most importantly, either an individual mark or a certain chrom

SUBMITTER: Pan X 

PROVIDER: S-EPMC5639768 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature