Cigarette smoking and the risk of nasopharyngeal carcinoma: a meta-analysis of epidemiological studies.

ABSTRACT:

Objective

The role of cigarette smoking as an independent risk factor for patients with nasopharyngeal carcinoma (NPC) is controversial. We attempted to provide evidence of a reliable association between cigarette smoking and the risk of NPC.

Design

Meta-analysis.

Data sources

PubMed online and the Cochrane Library of relevant studies published up to February 2016.

Eligibility criteria

All studies had to evaluate the relationship between NPC and cigarette smoking with never smokers as the reference group.

Outcomes

The primary outcome was the adjusted OR, RR or HR of NPC patients comparing smoking with never-smoking; the second was the crude OR, RR or HR.

Results

We identified 17 case-control studies and 4 cohort studies including 5960 NPC cases an

SUBMITTER: Long M 

PROVIDER: S-EPMC5640018 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature