Computer simulation models of pre-diabetes populations: a systematic review protocol.

ABSTRACT:

Introduction

Diabetes is a major public health problem and prediabetes (intermediate hyperglycaemia) is associated with a high risk of developing diabetes. With evidence supporting the use of preventive interventions for prediabetes populations and the discovery of novel biomarkers stratifying the risk of progression, there is a need to evaluate their cost-effectiveness across jurisdictions. In diabetes and prediabetes, it is relevant to inform cost-effectiveness analysis using decision models due to their ability to forecast long-term health outcomes and costs beyond the time frame of clinical trials. To support good implementation and reimbursement decisions of interventions in these populations, models should be clinically credible, based on best available evidence, reproducible

SUBMITTER: Leal J 

PROVIDER: S-EPMC5640045 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature