Haemodynamic response to crystalloids or colloids in shock: an exploratory subgroup analysis of a randomised controlled trial.

ABSTRACT:

Objective

To compare the haemodynamic effect of crystalloids and colloids during acute severe hypovolaemic shock.

Design

Exploratory subgroup analysis of a multicentre randomised controlled trial (Colloids Versus Crystalloids for the Resuscitation of the Critically Ill, CRISTAL, ClinicalTrials.gov NCT00318942).

Setting

CRISTAL was conducted in intensive care units in Europe, North Africa and Canada.

Participants

Current analysis included all patients who had a pulmonary artery catheter in place at randomisation. 220 patients (117 received crystalloids vs 103 colloids) underwent pulmonary artery catheterisation.

Intervention

Crystalloids versus colloids for fluid resuscitation in hypovolaemic shock.

Outcome measures

Haemodynamic data were collected

SUBMITTER: Heming N 

PROVIDER: S-EPMC5640079 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature