Fully implantable, battery-free wireless optoelectronic devices for spinal optogenetics.

ABSTRACT: The advent of optogenetic tools has allowed unprecedented insights into the organization of neuronal networks. Although recently developed technologies have enabled implementation of optogenetics for studies of brain function in freely moving, untethered animals, wireless powering and device durability pose challenges in studies of spinal cord circuits where dynamic, multidimensional motions against hard and soft surrounding tissues can lead to device degradation. We demonstrate here a fully implantable optoelectronic device powered by near-field wireless communication technology, with a thin and flexible open architecture that provides excellent mechanical durability, robust sealing against biofluid penetration and fidelity in wireless activation, thereby allowing for long-term optical st

SUBMITTER: Samineni VK 

PROVIDER: S-EPMC5640477 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature