Changes in acid-base and ion balance during exercise in normoxia and normobaric hypoxia.

ABSTRACT:

Purpose

Both exercise and hypoxia cause complex changes in acid-base homeostasis. The aim of the present study was to investigate whether during intense physical exercise in normoxia and hypoxia, the modified physicochemical approach offers a better understanding of the changes in acid-base homeostasis than the traditional Henderson-Hasselbalch approach.

Methods

In this prospective, randomized, crossover trial, 19 healthy males completed an exercise test until voluntary fatigue on a bicycle ergometer on two different study days, once during normoxia and once during normobaric hypoxia (12% oxygen, equivalent to an altitude of 4500 m). Arterial blood gases were sampled during and after the exercise test and analysed according to the modified physicochemical and Henderson-Hasse

SUBMITTER: Luhker O 

PROVIDER: S-EPMC5640730 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature