Fish oil supplementation does not lower C-reactive protein or interleukin-6 levels in healthy adults.

ABSTRACT:

Background

The n-3 polyunsaturated fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) may prevent a range of chronic conditions through anti-inflammatory actions. However, as clinical trials using these fatty acids for primary prevention are yet unavailable, their putative role in disease prevention rests, in part, on evidence of anti-inflammatory actions in healthy individuals.

Objective

To investigate in a double-blind, placebo-controlled clinical trial whether supplementation with a moderate dose of EPA+DHA reduces common biomarkers of chronic, systemic inflammation in healthy individuals.

Methods

A total of 261 healthy individuals aged 30-54 years who were free of inflammatory conditions and consumed ≤ 300 mg per day EPA+DHA were included in th

SUBMITTER: Muldoon MF 

PROVIDER: S-EPMC5642109 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature