Herpesviruses in etiopathogenesis of aggressive periodontitis: A meta-analysis based on case-control studies.

ABSTRACT: OBJECTIVE:Previous studies have found that herpesviruses are associated with aggressive periodontitis (AgP). However, these findings are controversial. This meta-analysis was aimed at clarifying the association between herpesviruses and AgP. METHODS:We identified eligible case-control studies evaluating the association between herpesviruses and AgP from PubMed and Embase databases in October 2015. Original data were extracted and quality assessment was done. Overall odds ratios (ORs) and 95% confidence intervals (CIs) were estimated. Random-effects model was determined. The stability was evaluated by sensitivity analysis. Finally, Egger's funnel plot was used to investigate the publication bias. RESULTS:Twelve case-control studies involving 322 patients and 342 controls were included in th

SUBMITTER: Li F 

PROVIDER: S-EPMC5643052 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature