Distinctive Gut Microbiota Is Associated with Diarrheagenic Escherichia coli Infections in Chilean Children.

ABSTRACT: Background: Diarrheagenic Escherichia coli (DEC) strains are a major cause of diarrhea in children under 5 years of age worldwide. DEC pathogenicity relies on the interaction of bacteria with environmental factors, including the host's resident gut microbiota. Previous reports have shown changes in the gut microbiota's composition during episodes of diarrhea, which may increase the pathogenicity of DEC strains. More intense and detailed identification of microbiota strains specifically associated with DEC infections and disease is needed to pinpoint their role in DEC pathogenicity. Aim: To identify resident indicative bacterial taxa in DEC-positive diarrhea stool samples of Chilean children. Methods: We analyzed 63 diarrheal stool samples from children 1-5 years

SUBMITTER: Gallardo P 

PROVIDER: S-EPMC5643428 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature