Elevation of serum uric acid and incidence of type 2 diabetes: A systematic review and meta-analysis.

ABSTRACT:

Objective

Recently, several cohort studies suggested a positive relationship between serum uric acid (SUA) and type 2 diabetes mellitus (T2DM), which is inconsistent with the results of functional research. Our aim was to further evaluate this correlation by conducting a systematic review.

Methods

Computerized literature searches of the Medline database, EMBASE database, and PubMed were used to evaluate the relationship between SUA and T2DM in cohort studies. Cochran's Q and I² statistics were used to evaluate heterogeneity among studies, and pooled relative risk (RR) and odds ratio (OR) with 95% confidence intervals (CIs) were calculated using random-effects and fixed-effects models. The summary RR and OR of per 1 

SUBMITTER: Xu YL 

PROVIDER: S-EPMC5643744 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature