Portable perfusion phantom for quantitative DCE-MRI of the abdomen.

ABSTRACT:

Purpose

The aim of this study was to develop a portable perfusion phantom and validate its utility in quantitative dynamic contrast-enhanced magnetic resonance imaging of the abdomen.

Methods

A portable perfusion phantom yielding a reproducible contrast enhancement curve (CEC) was developed. A phantom package including perfusion and static phantoms were imaged simultaneously with each of three healthy human volunteers in two different 3T MR scanners. Look-up tables correlating reference (known) contrast concentrations with measured ones were created using either the static or perfusion phantom. Contrast maps of image slices showing four organs (liver, spleen, pancreas, and paravertebral muscle) were generated before and after data correction using the look-up tables. The con

SUBMITTER: Kim H 

PROVIDER: S-EPMC5646228 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature