Origin and Spread of Spliceosomal Introns: Insights from the Fungal Clade Zymoseptoria.

ABSTRACT: Spliceosomal introns are a key feature of eukaryote genome architecture and have been proposed to originate from selfish group II introns from an endosymbiotic bacterium, that is, the ancestor of mitochondria. However, the mechanisms underlying the wide spread of spliceosomal introns across eukaryotic genomes have been obscure. In this study, we characterize the dynamic evolution of spliceosomal introns in the fungal genus Zymoseptoria at different evolutionary scales, that is, within a genome, among conspecific strains within species, and between different species. Within the genome, spliceosomal introns can proliferate in unrelated genes and intergenic regions. Among conspecific strains, spliceosomal introns undergo rapid turnover (gains and losses) and frequent sequence exchange between

SUBMITTER: Wu B 

PROVIDER: S-EPMC5647799 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature