Electrophysiological correlates of oxytocin-induced enhancement of social performance monitoring.

ABSTRACT: Altered performance monitoring has been demonstrated after administration of different pharmacological compounds and in various clinical populations, such as excessive neurophysiological responses to mistakes in anxiety disorders. Here, a novel social pharmacological approach was applied to investigate whether oxytocin administration (24 IU) enhances performance monitoring for errors that have negative consequences for another individual, so-called social mistakes. Healthy male volunteers (N = 24) participated in a placebo-controlled crossover design. EEG measures were obtained while pairs of participants performed a speeded choice reaction-time task in an individual and social context. Following oxytocin administration, error-related negativity amplitudes were increased for social compare

SUBMITTER: de Bruijn ERA 

PROVIDER: S-EPMC5647804 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature