CA 19-9 and CA 125 as potential predictors of disease recurrence in resectable lung adenocarcinoma.

ABSTRACT:

Objectives

Among patients who underwent primary surgery for non-small cell lung cancer (NSCLC), recurrent disease is frequent and cannot be accurately predicted solely from TNM stage and histopathological features. The aim of this study was to examine the association of tumor markers in pre-operative serum with recurrent disease.

Material and methods

Blood samples were collected prior to lung cancer surgery from 107 patients with stage I-III lung adenocarcinoma surgically treated at Lund University hospital, Lund, Sweden, between 2005 and 2011. The serum tumor markers Carcinoembryonic antigen (CEA), Neuron-specific enolase (NSE), Cancer antigen 125 (CA 125), Human epididymis protein 4 (HE4) and Carbohydrate antigen (CA 19-9) were analyzed retrospectively and clinical follow-

SUBMITTER: Isaksson S 

PROVIDER: S-EPMC5648153 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature