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SNP and Haplotype Analysis of Vascular Endothelial Growth Factor (VEGF) Gene in Lung Cancer Patients of Kashmir


ABSTRACT: Vascular endothelial growth factor (VEGF) is a major mediator of angiogenesis involving tumor growth and

SUBMITTER: Naikoo NA 

PROVIDER: S-EPMC5648382 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature

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SNP and Haplotype Analysis of Vascular Endothelial Growth Factor (VEGF) Gene in Lung Cancer Patients of Kashmir

Naikoo Niyaz A NA   Afroze Dil D   Rasool Roohi R   Shah Sonaullah S   Ahangar A G AG   Bhat Imtiyaz A IA   Qasim Iqbal I   Siddiqi Mushtaq A MA   Shah Zafar A ZA  

Asian Pacific journal of cancer prevention : APJCP 20170727 7


Vascular endothelial growth factor (VEGF) is a major mediator of angiogenesis involving tumor growth and metastasis. In this large case-control study, we investigated whether functional polymorphisms (+405C>G, +936C>T) in the VEGF gene are associated with the risk of lung cancer. The study investigates the association between variants of VEGF gene and lung cancer. We performed single nucleotide polymorphism (SNP), haplotype and linkage disequilibrium studies on 100 patients and 128 healthy contr  ...[more]

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