Ontology highlight
ABSTRACT:
SUBMITTER: Wu YZ
PROVIDER: S-EPMC5650302 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Wu Yi-Zhong YZ Tan Gao G Wu Fang F Zhi Fa-Chao FC
Oncotarget 20170518 43
There is an epidemiological inverse relationship between <i>Helicobacter pylori</i> (<i>H. pylori</i>) infection and Crohn's disease (CD). However, whether <i>H. pylori</i> plays a protective role against CD remains unclear. Since 2, 4, 6-trinitrobenzene sulfonic acid (TNBS)-induced colitis is thought to resemble CD, we investigated whether <i>H. pylori</i> can attenuate TNBS-induced colitis in mice. Here we show that <i>H. pylori</i> can attenuate the severity of TNBS-induced colitis. In additi ...[more]