Prognostic role of systemic immune-inflammation index in solid tumors: a systematic review and meta-analysis.

ABSTRACT:

Background

Inflammation may play an important role in cancer progression, and a higher systemic immune-inflammation index (SII) has been reported to be a poor prognostic marker in several malignancies. However, the results of published studies are inconsistent.

Materials and methods

A systematic review of databases was conducted to search for publications regarding the association between blood SII and clinical outcome in solid tumors with a date up to February 12, 2017. The primary outcome was overall survival (OS) and the secondary outcomes were progression-free survival (PFS) and cancer-specific survival (CSS). Pooled hazard ratios (HRs) and 95% confidence intervals (CIs) were used to assess the strength of the association between blood SII and clinical outcome in solid t

SUBMITTER: Zhong JH 

PROVIDER: S-EPMC5650428 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature