Lung Function and Incident Kidney Disease: The Atherosclerosis Risk in Communities (ARIC) Study.

ABSTRACT:

Background

Reduced lung function is associated with clinical outcomes such as cardiovascular disease. However, little is known about its association with incident end-stage renal disease (ESRD) and chronic kidney disease (CKD).

Study design

Prospective cohort study.

Setting & participants

14,946 participants aged 45 to 64 years at baseline (1987-1989) in the Atherosclerosis Risk in Communities (ARIC) Study (45.0% men and 25.2% black), with follow-up through 2012.

Predictors

Race- and sex-specific quartiles of percent-predicted forced vital capacity (FVC) and the proportion of forced expiratory volume in 1 second of expiration to FVC (FEV₁/FVC) at baseline determined with spirometry.

Outcomes

Incident ESRD (defined here as renal replacement the

SUBMITTER: Sumida K 

PROVIDER: S-EPMC5651181 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature