Changes in disease-specific versus generic health status measures after left ventricular assist device implantation: Insights from INTERMACS.

ABSTRACT:

Background

Quantifying quality of life (QoL) after left ventricular assist device (LVAD) remains challenging. Heart failure (HF)-specific health status measures are ideal for assessing symptoms of HF; however, if patients' QoL is limited by other factors, they may experience improved HF-specific QoL but no concurrent improvement in generic QoL. We sought to examine and predict discrepancies between disease-specific and generic QoL measures after LVAD.

Methods

We examined HF-specific and generic QoL with the Kansas City Cardiomyopathy Questionnaire (KCCQ) and EuroQol-5D Visual Analog Scale (VAS), respectively, among 1,888 patients with advanced heart failure who underwent LVAD implantation from 2012 to 2014 as part of the INTERMACS registry.

Results

Both measures showe

SUBMITTER: Nassif ME 

PROVIDER: S-EPMC5651195 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature