Mnemonic strategy training of the elderly at risk for dementia enhances integration of information processing via cross-frequency coupling.

ABSTRACT: INTRODUCTION:We sought to identify whether intensive 10-week mobile health mnemonic strategy training (MST) could shift the resting-state brain network more toward cortical-level integration, which has recently been proven to reflect the reorganization of the brain networks compensating the cognitive decline. METHODS:One hundred fifty-eight patients with mild cognitive impairment (MCI) were selected and participated in 10-week training lasting 90 min/d of memory training. They benefited from an initial and a follow-up neuropsychological evaluation and resting-state electroencephalography (EEG). RESULTS:At follow-up, MST revealed an extensive significant training effect that changed the network with an increase of synchronization between parietotemporal and frontal areas; frontalθ-parietalα

SUBMITTER: Dimitriadis SI 

PROVIDER: S-EPMC5651360 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature