Uncovering Active Constituents Responsible for Different Activities of Raw and Steamed Panax notoginseng Roots.

ABSTRACT: Although Panax notoginseng (PN) roots in raw and steamed forms were historically supposed to be different in the efficacies, the raw materials and steamed ones were often undifferentiated in the use and market circulation, which might bring unstable curative effects or even adverse reactions. To uncover chemical constituents responsible to different activities of raw and steamed PN, chemometrics analyses including partial least squares regression (PLSR) and multi-linear regression analysis (MLRA) were used to establish the relationships between the chromatographic fingerprints and activities of PN samples. Chemical fingerprints of PN were determined by HPLC. Anticoagulant and antioxidant activities were evaluated by the thromboplastin inhibiting test and hydroxyl radical scavenging assay,

SUBMITTER: Xiong Y 

PROVIDER: S-EPMC5651511 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature