Cellular Response to ELF-MF and Heat: Evidence for a Common Involvement of Heat Shock Proteins?

ABSTRACT: It has been shown that magnetic fields in the extremely low frequency range (ELF-MF) can act as a stressor in various in vivo or in vitro systems, at flux density levels below those inducing excitation of nerve and muscle cells, which are setting the limits used by most generally accepted exposure guidelines, such as the ones published by the International Commission on Non-Ionizing Radiation Protection. In response to a variety of physiological and environmental factors, including heat, cells activate an ancient signaling pathway leading to the transient expression of heat shock proteins (HSPs), which exhibit sophisticated protection mechanisms. A number of studies suggest that also ELF-MF exposure can activate the cellular stress response and cause increased HSPs expression, both on the

SUBMITTER: Zeni O 

PROVIDER: S-EPMC5651525 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature