Preliminary comparative genomics revealed pathogenic potential and international spread of Staphylococcus argenteus.

ABSTRACT:

Background

Staphylococcus argenteus and S. schweitzeri, were recently proposed as novel species within S. aureus complex (SAC). S. argenteus has been reported in many countries and can threaten human health. S. schweitzeri has not been associated with human infections, but has been isolated from non-human primates. Questions regarding the evolution of pathogenicity of these two species will remain elusive until an exploratory evolutionary framework is established.

Results

We present genomic comparison analysis among members of SAC based on a pan-genome definition, which included 15 S. argenteus genomes (five newly sequenced), six S. schweitzeri genomes and 30 divergent S. aureus genomes. The three species had divergent core genomes and rare interspecific recombination was ob

SUBMITTER: Zhang DF 

PROVIDER: S-EPMC5651615 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature