Immunosenescence patterns differ between populations but not between sexes in a long-lived mammal.

ABSTRACT: In animals, physiological mechanisms underlying reproductive and actuarial senescence remain poorly understood. Immunosenescence, the decline in the ability to display an efficient immune response with increasing age, is likely to influence both reproductive and actuarial senescence through increased risk of disease. Evidence for such a link has been reported from laboratory animal models but has been poorly investigated in the wild, where variation in resource acquisitions usually drives life-history trade-offs. We investigated immunosenescence patterns over 7 years in both sexes of two contrasting roe deer populations (Capreolus capreolus). We first measured twelve immune markers to obtain a thorough identification of innate and adaptive components of immunity and assessed, from the same

SUBMITTER: Cheynel L 

PROVIDER: S-EPMC5651810 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature