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Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru.


ABSTRACT: Because within-host Mycobacterium tuberculosis diversity complicates diagnosis and treatment of tuberculosis (TB), we measured diversity prevalence and associated factors among 3,098 pulmonary TB patients in Lima, Peru. The 161 patients with polyclonal infection were more likely than the 115 with clonal or the 2,822 with simple infections to have multidrug-resistant TB.

SUBMITTER: Nathavitharana RR 

PROVIDER: S-EPMC5652442 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature

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Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru.

Nathavitharana Ruvandhi R RR   Shi Cynthia X CX   Chindelevitch Leonid L   Calderon Roger R   Zhang Zibiao Z   Galea Jerome T JT   Contreras Carmen C   Yataco Rosa R   Lecca Leonid L   Becerra Mercedes C MC   Murray Megan B MB   Cohen Ted T  

Emerging infectious diseases 20171101 11


Because within-host Mycobacterium tuberculosis diversity complicates diagnosis and treatment of tuberculosis (TB), we measured diversity prevalence and associated factors among 3,098 pulmonary TB patients in Lima, Peru. The 161 patients with polyclonal infection were more likely than the 115 with clonal or the 2,822 with simple infections to have multidrug-resistant TB. ...[more]

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