Discrepancies between ClinicalTrials.gov recruitment status and actual trial status: a cross-sectional analysis.

ABSTRACT:

Objectives

To determine the accuracy of the recruitment status listed on ClinicalTrials.gov as compared with the actual trial status.

Design

Cross-sectional analysis.

Setting

Random sample of interventional phase 2-4 clinical trials registered between 2010 and 2012 on ClinicalTrials.gov.

Primary outcome measure

For each trial which was listed within ClinicalTrials.gov as ongoing, two investigators performed a comprehensive literature search for evidence that the trial had actually been completed. For each trial listed as completed or terminated early by ClinicalTrials.gov, we compared the date that the trial was actually concluded with the date the registry was updated to reflect the study's conclusion status.

Results

Among the 405 included trials, 92 ha

SUBMITTER: Jones CW 

PROVIDER: S-EPMC5652524 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature