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Comorbidity and outcomes in traumatic brain injury: protocol for a systematic review on functional status and risk of death.


ABSTRACT:

Introduction

Reports on the association between comorbidity and functional status and risk of death in patients with traumatic brain injury (TBI) have been inconsistent; it is currently unknown which additional clinical entities (comorbidities) have an adverse influence on the evolution of outcomes across the lifespan of men and women with TBI. The current protocol outlines a strategy for a systematic review of the current evidence examining the impact of comorbidity on functional status and early-term and late-term mortality, taking into account known risk factors of these adverse outcomes (ie, demographic (age and sex) and injury-related characteristics).

Methods and analysis

A comprehensive search strategy for TBI prognosis, functional (cognitive and physical) status and

SUBMITTER: Mollayeva T 

PROVIDER: S-EPMC5652528 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature