Long-term allograft and patient outcomes of kidney transplant recipients with and without incident cancer - a population cohort study.

ABSTRACT: The excess risk for cancer in kidney transplant recipients is substantial, but the allograft and patient survivals after cancer development are under-studied. This is a population-based cohort study of all primary live and deceased donor kidney transplant recipients in Australia and New Zealand between 1990-2012. The risks of overall graft loss and death with a functioning graft in kidney transplant recipients with and without incident cancer were determined using adjusted Cox regression analysis, with incident cancer considered as a time-varying covariate in the models. In those with incident cancer, types and cancer stage at diagnoses were reported. Of 12,545 transplant recipients followed for a median of 6.9 years (91,380 patient-years), 1184 (9.4%) developed incident cancers at a media

SUBMITTER: Lim WH 

PROVIDER: S-EPMC5652814 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature