Region and species dependent mechanical properties of adolescent and young adult brain tissue.

ABSTRACT: Traumatic brain injuries, the leading cause of death and disability in children and young adults, are the result of a rapid acceleration or impact of the head. In recent years, a global effort to better understand the biomechanics of TBI has been undertaken, with many laboratories creating detailed computational models of the head and brain. For these models to produce realistic results they require accurate regional constitutive data for brain tissue. However, there are large differences in the mechanical properties reported in the literature. These differences are likely due to experimental parameters such as specimen age, brain region, species, test protocols, and fiber direction which are often not reported. Furthermore, there is a dearth of reported viscoelastic properties for brain t

SUBMITTER: MacManus DB 

PROVIDER: S-EPMC5653834 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature