Randomised controlled pilot trial of an exercise plus behaviour change intervention in people with multiple sclerosis: the Step it Up study.

ABSTRACT:

Objective

To investigate feasibility of multiple sclerosis (MS) exercise guidelines for inactive people with MS (PwMS) and to examine preliminary efficacy for walking. To investigate effect of augmenting that intervention with education based on social cognitive theory (SCT).

Design

Pilot multicentre, double-blind, randomised, parallel, controlled trial.

Setting

Community-delivered programme.

Participants

Sixty-five physically inactive PwMS walked independently, scored 0-3 on the Patient Determined Disease Steps Scale, had no MS relapse or change in MS medication in 12 weeks.

Interventions

10-week exercise plus SCT education (SCT) compared with exercise plus attention control education (CON).

Outcome measures

Six-Minute Walk Test (6MWT), Timed Up

SUBMITTER: Hayes S 

PROVIDER: S-EPMC5654468 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature