Air pollution, weight loss and metabolic benefits of bariatric surgery: a potential model for study of metabolic effects of environmental exposures.

ABSTRACT:

Background

Emerging experimental evidence suggests that air pollution may contribute to development of obesity and diabetes, but studies of children are limited.

Objectives

We hypothesized that pollution effects would be magnified after bariatric surgery for treatment of obesity, reducing benefits of surgery.

Methods

In 75 obese adolescents, excess weight loss (EWL), high-density lipoprotein (HDL) cholesterol, triglycerides, alkaline phosphatase (ALP) and hemoglobin A1c (HbA_1c ) were measured prospectively at baseline and following laparoscopic adjustable gastric banding (LAGB). Residential distances to major roads and the average two-year follow-up exposure to particulate matter <2.5 μm (PM_2.5 ), nitrogen dioxide (NO₂ ) and ozone were

SUBMITTER: Ghosh R 

PROVIDER: S-EPMC5654694 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature