Chromosome-Mediated mcr-3 Variants in Aeromonas veronii from Chicken Meat.

ABSTRACT: Two adjacent colistin resistance gene variants, termed mcr-3.3 and mcr-3-like, were identified in the chromosome of an Aeromonas veronii isolate obtained from retail chicken meat. The variants showed 95.20% and 84.19% nucleotide sequence identity, respectively, to mcr-3 from porcine Escherichia coli Functional cloning indicated that only mcr-3.3 conferred polymyxin resistance in both E. coli and Aeromonas salmonicida The mcr-3.3-mcr-3-like segment was also observed in other Aeromonas species, including A. media, A. caviae, and A. hydrophila.

SUBMITTER: Ling Z 

PROVIDER: S-EPMC5655048 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature