Ontology highlight
ABSTRACT:
SUBMITTER: Park PG
PROVIDER: S-EPMC5655201 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Oncotarget 20170525 46
Colorectal cancer (CRC) is one of the most dangerous types of malignant tumors, and cancer metastasis is a major factor in the failure of CRC therapy. Recently, LOXL2 (lysyl oxidase-like 2) has been shown to represent a regulator of epithelial-mesenchymal transition (EMT) in different cancer types. However, LOXL2 has not been reported to be involved in CRC metastasis. In this study, we demonstrated that LOXL2 expression is strongly correlated with the rate of CRC metastasis, it participates in t ...[more]