Epstein-Barr virus infection and oral squamous cell carcinoma risk: A meta-analysis.

ABSTRACT:

Background

The evidence for association between Epstein-Barr virus (EBV) infection and risk of oral squamous cell carcinoma (OSCC) is inconsistent in the literature. Therefore, this meta-analysis was conducted to clarify this association.

Methods

A literature search was conducted in electronic databases for English- and Chinese-language publications until March 31, 2017 to include eligible case-control studies. The pooled odds ratio (OR) and 95% confidence interval (95% CI) were estimated to determine the association between EBV infection and OSCC risk using a fixed- or random-effects model based on heterogeneity. Publication bias was assessed using funnel plot analysis.

Results

A total of 13 case-control studies with 686 OSCC patients and 433 controls were included b

SUBMITTER: She Y 

PROVIDER: S-EPMC5655447 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature