Creating hemodynamic atlases of cardiac 4D flow MRI.

ABSTRACT:

Purpose

Hemodynamic atlases can add to the pathophysiological understanding of cardiac diseases. This study proposes a method to create hemodynamic atlases using 4D Flow magnetic resonance imaging (MRI). The method is demonstrated for kinetic energy (KE) and helicity density (H_d ).

Materials and methods

Thirteen healthy subjects underwent 4D Flow MRI at 3T. Phase-contrast magnetic resonance cardioangiographies (PC-MRCAs) and an average heart were created and segmented. The PC-MRCAs, KE, and H_d were nonrigidly registered to the average heart to create atlases. The method was compared with 1) rigid, 2) affine registration of the PC-MRCAs, and 3) affine registration of segmentations. The peak and mean KE and H_d before and after registration were

SUBMITTER: Cibis M 

PROVIDER: S-EPMC5655727 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature