Predictive biological markers of systemic lupus erythematosus flares: a systematic literature review.

ABSTRACT:

Background

The aim of this study was to identify the most reliable biomarkers in the literature that could be used as flare predictors in systemic lupus erythematosus (SLE).

Methods

A systematic review of the literature was performed using two databases (MEDLINE and EMBASE) through April 2015 and congress abstracts from the American College of Rheumatology and the European League Against Rheumatism were reviewed from 2010 to 2014. Two independent reviewers screened titles and abstracts and analysed selected papers in detail, using a specific questionnaire. Reports addressing the relationships between one or more defined biological test(s) and the occurrence of disease exacerbation were included in the systematic review.

Results

From all of the databases, 4668 records

SUBMITTER: Gensous N 

PROVIDER: S-EPMC5655881 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature