Associations between self-reported sleep quality and white matter in community-dwelling older adults: A prospective cohort study.

ABSTRACT: Both sleep disturbances and decline in white matter microstructure are commonly observed in ageing populations, as well as in age-related psychiatric and neurological illnesses. A relationship between sleep and white matter microstructure may underlie such relationships, but few imaging studies have directly examined this hypothesis. In a study of 448 community-dwelling members of the Whitehall II Imaging Sub-Study aged between 60 and 82 years (90 female, mean age 69.2 ± 5.1 years), we used the magnetic resonance imaging technique diffusion tensor imaging to examine the relationship between self-reported sleep quality and white matter microstructure. Poor sleep quality at the time of the diffusion tensor imaging scan was associated with reduced global fractional anisotropy and increased gl

SUBMITTER: Sexton CE 

PROVIDER: S-EPMC5655937 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature