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Tackling Cell Transplantation Anoikis: An Injectable, Shape Memory Cryogel Microcarrier Platform Material for Stem Cell and Neuronal Cell Growth.

ABSTRACT: Highly macroporous semisynthetic cryogel microcarriers can be synthesized for culturing stem cells and neuronal type cells. Growth factors loaded to heparin-containing microcarriers show near zero-order release kinetics and cell-loaded microcarriers can be injected through a fine gauge cannula without negative effect on the cells. These carriers can be applied for cell transplantation applications.

SUBMITTER: Newland B 

PROVIDER: S-EPMC5656175 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature

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Tackling Cell Transplantation Anoikis: An Injectable, Shape Memory Cryogel Microcarrier Platform Material for Stem Cell and Neuronal Cell Growth.

Newland Ben B   Welzel Petra B PB   Newland Heike H   Renneberg Claudia C   Kolar Petr P   Tsurkan Mikhail M   Rosser Anne A   Freudenberg Uwe U   Werner Carsten C  

Small (Weinheim an der Bergstrasse, Germany) 20150803 38

Highly macroporous semisynthetic cryogel microcarriers can be synthesized for culturing stem cells and neuronal type cells. Growth factors loaded to heparin-containing microcarriers show near zero-order release kinetics and cell-loaded microcarriers can be injected through a fine gauge cannula without negative effect on the cells. These carriers can be applied for cell transplantation applications. ...[more]

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