Inversed-Planned Respiratory Phase Gating in Lung Conformal Radiation Therapy.

ABSTRACT:

Purpose

To assess whether the optimal gating window for each beam during lung radiation therapy with respiratory gating will be dependent on a variety of patient-specific factors, such as tumor size and location and the extent of relative tumor and organ motion.

Methods and materials

To create optimal gating treatment plans, we started from an optimized clinical plan, created a plan per respiratory phase using the same beam arrangements, and used an inverse planning optimization approach to determine the optimal gating window for each beam and optimal beam weights (ie, monitor units). Two pieces of information were used for optimization: (1) the state of the anatomy at each phase, extracted from 4-dimensional computed tomography scans; and (2) the time spent in each state, e

SUBMITTER: Modiri A 

PROVIDER: S-EPMC5656395 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature