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Hypothyroidism as a risk factor for open angle glaucoma: A systematic review and meta-analysis.


ABSTRACT:

Purpose

The relationship between hypothyroidism and primary open angle glaucoma (POAG) has attracted intense interest recently, but the reported results have been controversial. This meta-analysis was carried out to determine the association between hypothyroidism and POAG.

Methods

The literature was identified from three databases (Web of Science, Embase, and PubMed). The meta-analyses were performed using random-effects models, with results reported as adjusted odds ratios (ORs) with 95% confidence intervals (CI 95%).

Results

A total of 11 studies meeting the inclusion criteria were included in the final meta-analysis. The pooled OR based on 11 risk estimates showed a statistically significant increased risk of POAG prevalence among individuals with hypothyroidism (

SUBMITTER: Wang S 

PROVIDER: S-EPMC5656411 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature