Demographics and natural history of HIV-1-infected spontaneous controllers of viremia.

ABSTRACT:

Objectives

HIV-1-infected persons spontaneously controlling viremia without treatment (SCV) are rare. Sex and race effects on prevalence and outcome are poorly defined, and it is unclear whether SCV qualitatively or quantitatively differs from typical infection. These issues are examined in this article.

Design

Medical records of 46 524 persons receiving outpatient care for HIV-1 infection were reviewed. Of these, 29 811 had adequate viremia testing for SCV screening.

Methods

SCV was defined as at least three consecutive plasma viremia measurements <50 RNA copies/ml spanning at least 1 year without treatment. SCV loss was defined as at least three consecutive viremia measurements ≥50 RNA copies/ml or one ≥1000 RNA copies/ml. Demographics of persons with SCV were compa

SUBMITTER: Yang OO 

PROVIDER: S-EPMC5657480 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature