Testing for hepatitis B virus alone does not increase vaccine coverage in non-immunized persons.

ABSTRACT:

Aim

To determine whether hepatitis B virus (HBV)-testing could serve as a gateway to vaccinate non-immunized individuals in a low-prevalent country.

Methods

Non-immunized subjects participating in a multi-center, HBV-testing campaign in Paris, France were identified and contacted via telephone 3-9 mo after testing in order to determine vaccination status. Vaccination coverage was evaluated in per-protocol (for all respondents) and intent-to-treat analysis (assuming all non-responders did not vaccinate).

Results

In total, 1215/4924 (24.7%) enrolled subjects with complete HBV serology were identified as non-immunized and eligible for analysis. There were 99/902 successfully contacted subjects who had initiated HBV vaccination after screening: per-protocol, 11.0% (95%CI:

SUBMITTER: Boyd A 

PROVIDER: S-EPMC5658321 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature