Reducing the critical particle diameter in (highly) asymmetric sieve-based lateral displacement devices.

ABSTRACT: Deterministic lateral displacement technology was originally developed in the realm of microfluidics, but has potential for larger scale separation as well. In our previous studies, we proposed a sieve-based lateral displacement device inspired on the principle of deterministic lateral displacement. The advantages of this new device is that it gives a lower pressure drop, lower risk of particle accumulation, higher throughput and is simpler to manufacture. However, until now this device has only been investigated for its separation of large particles of around 785 µm diameter. To separate smaller particles, we investigate several design parameters for their influence on the critical particle diameter. In a dimensionless evaluation, device designs with different geometry and dimensions were

SUBMITTER: Dijkshoorn JP 

PROVIDER: S-EPMC5658425 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature